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In my previous blog posts I’ve talked about various potential applications of Salvia, such as an antidepressant or a treatment for addiction. Another large area of research into this unique plant is focussed on investigating the analgesic (painkilling) properties of Salvinorin A, the main psychedelic constituent of Salvia.

A common issue with modern painkillers is the fact that they are often very addictive. Many effective painkillers, such as morphine or codeine, are mu-opioid receptor (MOR) activators. Addiction can result from improper use of opioids like morphine. An ideal painkiller would relieve pain without causing this addiction; this is where the potential of Salvinorin A comes in.

Firstly, I’m going to look at a paper that examines the analgesic properties of Salvinorin A, and presents some of the issues that may arise from using Salvinorin A as a painkiller. Then we’ll look at the remaining challenges scientists face before Salvinorin A research can lead to an effective painkilling drug, and how these challenges are already being met.

Just a quick update to say we've got rid of our old contact form as it wasn't working very well. From now, the best way to contact us is via email at [email protected] and we'll respond as soon as we can! You can also reply directly to any of the automatically generated emails sent when placing an order or signing up for an account.

You can also always get customer support via our Twitter or Facebook pages.

Recent statistics show a neglegible rise in the number of legal highs deaths, and everyone loses their minds!

The numbers have JUMPED up from 51 in 2011 to a whopping 68 in 2012. In response to the usual outrage when this sort of thing is reported, I have prepared a graph, putting these numbers in their rightful place:

Note: I couldn't find alcohol stats for 2012, so I averaged the previous years. If anyone can find me the right number, I'll update the graph.

A slightly more interesting note: "Legal Highs" is actually referring to "New Psychoactive Substances". A co-author of the report mentions that 80% of "legal highs" deaths shown in this graph are actually related to chemicals that have already been banned.

Make of that what you will!

We're running a massive competition this month to give away 10 whole entire grams of squidgy black! My god! If you want in, head on over to our Competition page. It's so easy to enter, you don't even need to get dressed.

I got back off holiday earlier this month to discover our site had been down for several days. Anyone with any experience running websites will know just how much of a pain in the arse dealing with a server can be. Well, I’ve been working long and hard since we’ve been back to fix the problem, make sure it doesn’t happen again and speed things up a bit.

As a higher IQ is associated with drug use, I hope you can forgive the departure from the usual topics found on our blog while I talk about some nerdy server-related stuff for a bit!

“A new review of "legal highs" could lead to sweeping changes to UK drug legislation, the Home Office has said.” - BBC News

It looks like the government will be reviewing its ridiculously-out-of-date drug laws in the spring of 2014, possibly introducing new legislation  to ban legal highs that are “substantially similar” to already illegal substances. If they can pull it off, it just might work. Well, it will work in the sense that it will make it difficult to buy legal highs online and in headshops, which seems to be the intended goal. What it won’t do is make anyone safer. Far from it!

Read on to find out why this law is a bad idea and why your drug dealer totally sucks!

Good news, everyone! We now offer international shipping to a handful of countries within the EU!

At the moment, we can now ship to the following countries: UK, France, Spain, Poland The Netherlands, Jersey, The Isle of Man and Gibraltar

A new reseach paper, published on 19^th August, compared 21,967 users of "psychedlic drugs" with a representative sample of the population (130,152 total) to determine the effects of LSD, psilocybin and peyote on mental health.

Have a guess at what they found...

It feels like this country's youngsters are constantly in hospital after tangling with legal highs. Every day, there's another story in the news. Or rather, a rehash of the same couple of stories. Still, if it's all over the media, it must be important, right? Kids today are spiraling out of control and legal highs are to blame! We must obviously ban them!

Well, not quite.

Does this torn Rizla packet look familiar? If so, you sicken me.

You need to stop rolling joints like a savage and learn how to use roach cards!